Ocular findings in a case of haemoglobin H disease.

Ocular findings in a case of haemoglobin H disease.

A case is reported of a patient with known haemoglobin H disease who was found to have angioid streaks and retinal detachment. Angioid streaks have not previously been reported in cases of alpha-thalassaemia, and the question whether this is a chance association or otherwise is discussed.

Haemoglobin-H disease.

Liver in haemoglobin H disease.

There have been no published reports on the liver of patients with haemoglobin H disease. In 11 Chinese patients studied (six male and five female) with haemoglobin H disease hepatic function and histology were studied. Liver function was normal in all cases; however, the gamma globulin level was raised in four cases, the increase being mainly in IgG in all cases and IgA in six cases. Liver his...

Ocular findings in a case of fucosidosis.

The ocular findings in a case of fucosidosis are described and the differential diagnosis is discussed. It is suggested that the level of alpha-L-fucosidase should be estimated in cases of bull's eye retinopathy.

Ocular findings in children with sickle cell haemoglobin C disease in Jamaica.

The development of severe retinal vascular disease and retinitis proliferans in sickle cell haemoglobin C disease (SC disease) is well recognized (Welch and Goldberg, I966; Goldberg, 197I; Condon and Serjeant, I972a). In a recent survey in Jamaica, Condon and Serjeant (1972a) noted retinitis proliferans in 23 (33 per cent.) of seventy adults with SC disease. The changes were found in some patie...